puga :
Toxicity studies:
- Regular chewing of bettle nut is harmful to the health.It should be used in recommended dose only for medicinal purpose.
- Excessive chewing of nuts causes harm to your teeth.
- It is contra-indicated to Asthamatic patient (due to bronchoconstrictive effects of alkaloid arecoline) and pregnancy(due to Abortifacient effect)
- Due to increased incidence of oral cancer associated with betel chewing,it must not be used as masticatory.
- The seeds are fatally toxic at 8-10gm,fluid extract at 3.5l
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