Leaves contain amentoflavone. Stem bark extract gave positive tests for steroids, terpenes, alkaloids, flavonoids and saponins. An euphane triterpene 

alcohol has been isolated from this plant . Two diarylheptanoids, 6-Hydroxygaruganin and Garuganin were isolated from G. pinnata .Pheophorbide-α and-β methyl esters which are isolated from methanol crude extracts of this plant are reported paramount cytotoxic activity against KB and its drug resistant human cancer cell lines Garuganins I and II compounds isolated stem bark hot petrol and methanol extracts exhibits analogous mechanisms of antibacterial action