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Researches and clinical trials on trivrit - Ipomoea turpethum Linn..

trivrit :

Trivrit: Operculina turpethum Linn - Flower with fruit


Clinical trials:

Human Erythrocyte membrane stabilizing activity of 
Operculina turpethum.

Formation of strong anti-viral protein by Operculina
 turpenthum L. tissues in culture medium.
Presented in World Congress on Biotech Dev. Med. Subs. Plants & Marine Origin held at King George Medical College, Lucknow (India). M.M. Abid Ali Khan & N. Singh. 1995.

Purification and characterization of a low molecular weight anti-viral protein from Operculina turpethum L.M.M. Presented in World Congress on Biotech Dev. Med. Subs. Plants & Marine Origin held at King George Medical College, Lucknow (India). M.M. Abid Ali Khan and N. Singh. 1995.


Alcoholic extracts of fresh fruit of O.turpethum showed
 anti bacterial activity against Micrococcus pyogenes var.
 and E. coli
(Wealth of India, 1966, Raw materials, Vol VII, 96-97)

The ethanolic aqous & ethereal extracts ofOperculina
turpethum roots showed anti-inflammatory actvity 
against carrageenin inducted at rat paw edema as well as cotton pallet induced granuloma and formalin- induced arthritis in rat. The aquous extracts was found to be most potent fraction all three model of experimaental inflammation(Khare and team, A priliminary study of anti inflammatory activity of Ipomea turpethum (Nisoth))


Research:

Protective effect of root extract of Operculina 
turpethum linn. Against paracetamol-induced hepatotoxicity in rats.
Suresh Kumar S V and Team
Department of Pharmacognosy, Sri Padmavathi School of Pharmacy, Tirupati-517 501 
India
The ethanolic extract obtained from roots of Operculina turpethum (Convolvulaceae) were evaluated for hepatoprotective activity in rats by inducing liver damage by paracetamol. The ethanol extract at an oral dose of 200 mg/kg exhibited a significant protective effect by lowering serum levels of glutamic oxaloacetic transaminase, glutamic pyruvic transaminase, alkaline phosphatase and total bilirubin. These biochemical observations were supplemented by histopathological examination of liver sections. Silymarin was used as positive control.



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