giriparpat :
Rasa: Katu Tikta Guna: Laghu Teeskhsna
Veerya: Ushna
Vipaka: Katu
Karma: Pittahara
Podophyllotoxin is the major lignan present in the resin and is a dimerized product of the intermediates of the phenylpropanoid pathway. The starting material of etoposide (Vepeside), an FDA approved anticancer drug is podophyllotoxin and has been used to treat testicular cancer as well as lung cancer by inhibiting replication of cancer cells. Podophyllotoxin finds use as a precursor for the semi-synthetic topoisomerase inhibitors in the treatment of leukemias, lung and testicular cancers, dermatological disorders like warts, rheumatoid arthritis and psoriasis. It also has numerous applications in modern medicine by virtue of its free radical scavenging capacity.
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