Breast-feeding mothers should also avoid using myrrh. Not enough is known about the safety of using myrrh when breast-feeding.

Diabetes: Myrrh might lower blood sugar. There is a concern that if it is used along with medications that lower blood sugar, blood sugar might drop too low. If you use myrrh as well as medications for diabetes, monitor your blood sugar carefully.

Fever: Myrrh might make a fever worse. Use with caution.

Heart problems: Large amounts of myrrh can affect heart rate. If you have a heart condition, get your healthcare provider’s advice before starting myrrh.

Surgery: Since myrrh might affect blood glucose levels, there is a concern that it might interfere with blood glucose control during and after surgery. Stop using myrrh at least 2 weeks before a scheduled surgery.

Systemic inflammation: If you have systemic inflammation, use myrrh with caution, since it might make this condition worse.

Uterine bleeding: Myrrh seems to be able to stimulate uterine bleeding, which is why some women use it to start their menstrual periods. If you have a uterine bleeding condition, use myrrh with caution, since it might make this condition worse

Myrrh seems safe for most people when used in small amounts. It can cause some side effects such as skin rash if applied directly to the skin, and diarrhea if taken by mouth.

Large doses may be UNSAFE. Amounts greater than 2-4 grams can cause kidney irritation and heart rate changes.