Agaru is likely safe when used in the recommend dosage. There are no toxicity observed for its uses in patients suffering from any respiratory diseases or digestive ailment. However, it increases heat in the body thats why it is indicated in fever with chills. 

Some patients with pitha prakrthi or suffering from increased pitha dosha can have the following side effects:

- Feeling of excess heat in the body.

- Hyperacidity.