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Researches and clinical trials on Saptachakra - Salacia reticulata ..

Saptachakra:

vairi  : Salacia reticulata Wight


Research:

Anti- obesity effect: The extracts of Salacia reticulata (Salacia extract), a plant that has been used for the treatment of early diabetes, rheumatism and gonorrhea in Ayurveda, have been shown to have an anti-obesity effect and suppress hyperglycemia. In this study, the effects of Salacia extract on various symptoms of metabolic disorder were investigated and compared using these TSOD mice and non-obese TSNO mice.

Anti- diabetic and Anti- hyperlipidemic effect:  In human studies, Salacia extracts have been shown to decrease plasma glucose and insulin levels, decrease HbA1c, and modulate serum lipid levels with no adverse effects being reported. Similar results have been demonstrated in rat and mouse models as well as in vitro systems.

Anti diabetic and Anti obesity effect: Salacia sps belong to family Celastacea have prominent place in plant based medicine because it is used in management of diabetes and obesity. Salacia sps contain salacinol, katnanol, mangiferin are active principles which inhibit ?-glucosidase enzyme and slow down the absorption of glucose in intestine. Salacia species possess many therapeutic properties like anti-obesity, anti-diabetic etc.

The root extract of Salacia reticulata Wight (family: Celastraceae) is used in Sri Lanka by traditional practitioners as a herbal therapy for glycemic control even during pregnancy. It is recognized that some clinically used anti-diabetic drugs have harmful effects on pregnancy but the effects of the S. reticulata root extract on reproductive outcome is unknown and deserves examination. The authors of this article determined the effects of the S. reticulata root extract on the reproductive outcome of Wistar rats (250-260 g) when administered orally (10 g/kg) during early (days 1-7) and mid- (days 7-14) pregnancy. The root extract significantly (P<0.05) enhanced post-implantation losses
We conclude that the S. reticulata root extract can be hazardous to successful pregnancy in women and should not be used in pregnancy complicated by diabetes.

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