kutaja :

According to one study, Kutaj seed and bark is capable to kill free living amoebae and it also kills entamoeba histolytica in the dysenteric stools of experimentally infected kittens and the herb is markedly lethal to the flagellate protozoon. The strong antibacterial activity of the Holarrhena antidysenterica extract inhibits growth of enteropathogenic Escherichia coli(EPEC) bacteria strains. The EPEC strains are notorious for resisting the activities of multiple antibiotic drugs. The effectiveness of Holarrhena antidysenterica in treating diarrhea induced by EPEC strains makes it an effective alternative to conventional antibiotic drugs used for treating dysentery. The medicinal plant could also inhibit formation of bloody stools, a symptom of entero haemorrhagic Escherichia coli(EHEC) infection. Studies suggest that Holarrhena antidysenterica prevents and treats EPEC infections by prevented bacterial adhesion. The anti-adherence effect of the alkaloids of the herb provides a rational basis for treating diarrhea induced by EPEC infection.

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